If I were to ask you to identify the most significant medical breakthrough in the past 150 years, how would you answer For most of us we immediately think of high-profile medical advances, such as the discovery of penicillin and antibiotics, or the invention of the X-ray, the realization that we are products of a basic structure called DNA, the elimination of major disease processes such as smallpox, plague, and others, or the incredible life-saving virtues of automatic de-fibrillation, transplants, and others